T-cell responses targeting HIV Nef uniquely correlate with infected cell frequencies after long-term antiretroviral therapy

HIV-specific CD8(+) T-cell responses limit viral replication in untreated infection. After the initiation of antiretroviral therapy (ART), these responses decay and the infected cell population that remains is commonly considered to be invisible to T-cells. We hypothesized that HIV antigen recogniti...

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Dades bibliogràfiques
Publicat a:PLoS Pathog
Autors principals: Thomas, Allison S., Jones, Kimberley L., Gandhi, Rajesh T., McMahon, Deborah K., Cyktor, Joshua C., Chan, Dora, Huang, Szu-Han, Truong, Ronald, Bosque, Alberto, Macedo, Amanda B., Kovacs, Colin, Benko, Erika, Eron, Joseph J., Bosch, Ronald J., Lalama, Christina M., Simmens, Samuel, Walker, Bruce D., Mellors, John W., Jones, R. Brad
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5624641/
https://ncbi.nlm.nih.gov/pubmed/28931091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006629
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