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T cells with high PD-1 expression are associated with lower HIV-specific immune responses despite long-term antiretroviral therapy

OBJECTIVE. We evaluated frequencies of T cells with high PD-1 expression (PD-1(HI)) before and after long-term effective antiretroviral therapy (ART), and determined if frequencies on-ART correlated positively with measures of HIV persistence and negatively with HIV-specific responses. METHODS. We e...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:AIDS
Asıl Yazarlar: MACATANGAY, Bernard JC, GANDHI, Rajesh T, JONES, R Brad, MCMAHON, Deborah K, LALAMA, Christina M, BOSCH, Ronald J, CYKTOR, Joshua C, THOMAS, Allison S, BOROWSKI, Luann, RIDDLER, Sharon A, HOGG, Evelyn, STEVENSON, Eva, ERON, Joseph J, MELLORS, John W, RINALDO, Charles R
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7313719/
https://ncbi.nlm.nih.gov/pubmed/31634201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000002406
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