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5-aza-2′,2′-Difluroro Deoxycytidine (NUC013): A Novel Nucleoside DNA Methyl Transferase Inhibitor and Ribonucleotide Reductase Inhibitor for the Treatment of Cancer

Tumor suppressor genes can be silenced genetically as well as epigenetically. One approach to reversing epigenetic suppression of tumor suppressor genes is to inhibit DNA methyl transferase. 5-aza-2′,2′-diflurorodeoxycytidine (NUC013) is a novel DNA methyl transferase and ribonucleotide reductase in...

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Detaylı Bibliyografya
Yayımlandı:Pharmaceuticals (Basel)
Asıl Yazarlar: Daifuku, Richard, Hu, Zhenbo, Saunthararajah, Yogen
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5620609/
https://ncbi.nlm.nih.gov/pubmed/28726739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph10030065
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