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5-aza-2′,2′-Difluroro Deoxycytidine (NUC013): A Novel Nucleoside DNA Methyl Transferase Inhibitor and Ribonucleotide Reductase Inhibitor for the Treatment of Cancer

Tumor suppressor genes can be silenced genetically as well as epigenetically. One approach to reversing epigenetic suppression of tumor suppressor genes is to inhibit DNA methyl transferase. 5-aza-2′,2′-diflurorodeoxycytidine (NUC013) is a novel DNA methyl transferase and ribonucleotide reductase in...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Pharmaceuticals (Basel)
Egile Nagusiak: Daifuku, Richard, Hu, Zhenbo, Saunthararajah, Yogen
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5620609/
https://ncbi.nlm.nih.gov/pubmed/28726739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph10030065
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