Tumor antigen glycosaminoglycan modification regulates antibody-drug conjugate delivery and cytotoxicity

Aggressive cancers are characterized by hypoxia, which is a key driver of tumor development and treatment resistance. Proteins specifically expressed in the hypoxic tumor microenvironment thus represent interesting candidates for targeted drug delivery strategies. Carbonic anhydrase (CAIX) has been...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Oncotarget
Egile Nagusiak: Christianson, Helena C., Menard, Julien A., Indira Chandran, Vineesh, Bourseau-Guilmain, Erika, Shevela, Dmitry, Lidfeldt, Jon, Månsson, Ann-Sofie, Pastorekova, Silvia, Messinger, Johannes, Belting, Mattias
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Impact Journals LLC 2017
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5620149/
https://ncbi.nlm.nih.gov/pubmed/28978009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16921
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