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Tumor antigen glycosaminoglycan modification regulates antibody-drug conjugate delivery and cytotoxicity
Aggressive cancers are characterized by hypoxia, which is a key driver of tumor development and treatment resistance. Proteins specifically expressed in the hypoxic tumor microenvironment thus represent interesting candidates for targeted drug delivery strategies. Carbonic anhydrase (CAIX) has been...
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| Pubblicato in: | Oncotarget |
|---|---|
| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Impact Journals LLC
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5620149/ https://ncbi.nlm.nih.gov/pubmed/28978009 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16921 |
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