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Human CD3+ T-Cells with the Anti-ERBB2 Chimeric Antigen Receptor Exhibit Efficient Targeting and Induce Apoptosis in ERBB2 Overexpressing Breast Cancer Cells

Breast cancer is a common malignancy among women. The innate and adaptive immune responses failed to be activated owing to immune modulation in the tumour microenvironment. Decades of scientific study links the overexpression of human epidermal growth factor receptor 2 (ERBB2) antigen with aggressiv...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Munisvaradass, Rusheni, Kumar, Suresh, Govindasamy, Chandramohan, Alnumair, Khalid S., Mok, Pooi Ling
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5618474/
https://ncbi.nlm.nih.gov/pubmed/28885562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18091797
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