Human Tumor Growth Suppression by Apoptosis Induced with Anti‐ErbB‐2 Chimeric Monoclonal Antibody

We established an anti‐ErbB‐2 mouse‐human chimeric monoclonal antibody (MoAb), CH401, which was able to kill cancer cells overexpressing the ErbB‐2 protein in vitro. The analysis of the killing mechanism indicated that MoAb CH401 might be the first anti‐ErbB‐2 mouse‐human chimeric MoAb which can ind...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Sasaki, Shigeru, Tsujisaki, Masayuki, Jinnohara, Tsuneharu, Ishida, Tadao, Sekiya, Masuo, Adachi, Masaaki, Takahashi, Shuji, Hinoda, Yuji, Imai, Kohzoh
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 1998
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921853/
https://ncbi.nlm.nih.gov/pubmed/9685861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1998.tb03298.x
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