Human Tumor Growth Suppression by Apoptosis Induced with Anti‐ErbB‐2 Chimeric Monoclonal Antibody

We established an anti‐ErbB‐2 mouse‐human chimeric monoclonal antibody (MoAb), CH401, which was able to kill cancer cells overexpressing the ErbB‐2 protein in vitro. The analysis of the killing mechanism indicated that MoAb CH401 might be the first anti‐ErbB‐2 mouse‐human chimeric MoAb which can ind...

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Pubblicato in:Jpn J Cancer Res
Autori principali: Sasaki, Shigeru, Tsujisaki, Masayuki, Jinnohara, Tsuneharu, Ishida, Tadao, Sekiya, Masuo, Adachi, Masaaki, Takahashi, Shuji, Hinoda, Yuji, Imai, Kohzoh
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 1998
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921853/
https://ncbi.nlm.nih.gov/pubmed/9685861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1998.tb03298.x
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