Selective Inhibition of Tumor Growth by Clonal NK Cells Expressing an ErbB2/HER2-Specific Chimeric Antigen Receptor

Natural killer (NK) cells are an important effector cell type for adoptive cancer immunotherapy. Similar to T cells, NK cells can be modified to express chimeric antigen receptors (CARs) to enhance antitumor activity, but experience with CAR-engineered NK cells and their clinical development is stil...

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Vydáno v:Mol Ther
Hlavní autoři: Schönfeld, Kurt, Sahm, Christiane, Zhang, Congcong, Naundorf, Sonja, Brendel, Christian, Odendahl, Marcus, Nowakowska, Paulina, Bönig, Halvard, Köhl, Ulrike, Kloess, Stephan, Köhler, Sylvia, Holtgreve-Grez, Heidi, Jauch, Anna, Schmidt, Manfred, Schubert, Ralf, Kühlcke, Klaus, Seifried, Erhard, Klingemann, Hans G, Rieger, Michael A, Tonn, Torsten, Grez, Manuel, Wels, Winfried S
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445620/
https://ncbi.nlm.nih.gov/pubmed/25373520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2014.219
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