ERBB2/HER2-SPECIFIC NATURAL KILLER CELLS FOR ADOPTIVE IMMUNOTHERAPY OF GLIOBLASTOMA

BACKGROUND: While EGFRvIII appears a logical target for immunotherapy, only a subpopulation of tumor cells express EGFRvIII and immune escape has been demonstrated. ErbB2 is overexpressed in a substantial proportion of glioblastomas and has been successfully utilized in immunotherapies. Natural kill...

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Hlavní autoři: Steinbach, Joachim P., Zhang, Congcong, Burger, Michael, Jennewein, Lukas, Schönfeld, Kurt, Genßler, Sabrina, Sahm, Christiane, Brendel, Christian, Naundorf, Sonja, Odendahl, Marcus, Köhl, Ulrike, Nowakowska, Paulina, Seifried, Erhard, Bönig, Halvard, Tonn, Torsten, Grez, Manuel, Mittelbronn, Michel, Wels, Winfried S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144659/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou209.9
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