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Anti-ERBB2 sh-RNA Suppress Cell Growth in ERBB2-Overexpressing Upper Gastrointestinal Adenocarcinomas
INTRODUCTION: ERBB2 is overexpressed in 15–25% of upper gastrointestinal adenocarcinomas. We use a stable lentiviral shRNA model to demonstrate that ERBB2 suppression in upper gastrointestinal adenocarcinomas with documented ERBB2 amplification effectively decreases ERBB2 protein levels and decrease...
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| Vydáno v: | J Gastrointest Surg |
|---|---|
| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5093911/ https://ncbi.nlm.nih.gov/pubmed/19813066 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11605-009-0957-9 |
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