Dual role of mitochondria in producing melatonin and driving GPCR signaling to block cytochrome c release

G protein-coupled receptors (GPCRs) are classically characterized as cell-surface receptors transmitting extracellular signals into cells. Here we show that central components of a GPCR signaling system comprised of the melatonin type 1 receptor (MT(1)), its associated G protein, and β-arrestins are...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Suofu, Yalikun, Li, Wei, Jean-Alphonse, Frédéric G., Jia, Jiaoying, Khattar, Nicolas K., Li, Jiatong, Baranov, Sergei V., Leronni, Daniela, Mihalik, Amanda C., He, Yanqing, Cecon, Erika, Wehbi, Vanessa L., Kim, JinHo, Heath, Brianna E., Baranova, Oxana V., Wang, Xiaomin, Gable, Matthew J., Kretz, Eric S., Di Benedetto, Giulietta, Lezon, Timothy R., Ferrando, Lisa M., Larkin, Timothy M., Sullivan, Mara, Yablonska, Svitlana, Wang, Jingjing, Minnigh, M. Beth, Guillaumet, Gérald, Suzenet, Franck, Richardson, R. Mark, Poloyac, Samuel M., Stolz, Donna B., Jockers, Ralf, Witt-Enderby, Paula A., Carlisle, Diane L., Vilardaga, Jean-Pierre, Friedlander, Robert M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2017
Konular:
PNAS Plus
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5617277/
https://ncbi.nlm.nih.gov/pubmed/28874589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1705768114
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