Mutations Located outside the Integrase Gene Can Confer Resistance to HIV-1 Integrase Strand Transfer Inhibitors

Resistance to the integrase strand transfer inhibitors raltegravir and elvitegravir is often due to well-identified mutations in the integrase gene. However, the situation is less clear for patients who fail dolutegravir treatment. Furthermore, most in vitro experiments to select resistance to dolut...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:mBio
Prif Awduron: Malet, Isabelle, Subra, Frédéric, Charpentier, Charlotte, Collin, Gilles, Descamps, Diane, Calvez, Vincent, Marcelin, Anne-Geneviève, Delelis, Olivier
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2017
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5615196/
https://ncbi.nlm.nih.gov/pubmed/28951475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00922-17
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