CKS Proteins Promote Checkpoint Recovery by Stimulating Phosphorylation of Treslin

CKS proteins are small (9-kDa) polypeptides that bind to a subset of the cyclin-dependent kinases. The two paralogs expressed in mammals, Cks1 and Cks2, share an overlapping function that is essential for early development. However, both proteins are frequently overexpressed in human malignancy. It...

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Détails bibliographiques
Publié dans:Mol Cell Biol
Auteurs principaux: Mu, Ruiling, Tat, John, Zamudio, Robert, Zhang, Yaoyang, Yates, John R., Kumagai, Akiko, Dunphy, William G., Reed, Steven I.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2017
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5615187/
https://ncbi.nlm.nih.gov/pubmed/28739856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00344-17
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