Cks Overexpression Enhances Chemotherapeutic Efficacy by Overriding DNA Damage Checkpoints

Cks1 and Cks2 are adaptor-like proteins that bind many cyclin-dependent kinases (Cdks). A wealth of clinical data has shown that Cks proteins are overexpressed in many types of human cancers and this often correlates with increased tumor aggressiveness. Previously, we showed that Cks overexpression...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: del Rincón, Sonia V., Widschwendter, Martin, Sun, Dahui, Ekholm-Reed, Susanna, Tat, John, Teixeira, Leonardo K., Ellederova, Zdenka, Grolieres, Elise, Reed, Steven I., Spruck, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4245389/
https://ncbi.nlm.nih.gov/pubmed/24858038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.137
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