Cks Overexpression Enhances Chemotherapeutic Efficacy by Overriding DNA Damage Checkpoints

Cks1 and Cks2 are adaptor-like proteins that bind many cyclin-dependent kinases (Cdks). A wealth of clinical data has shown that Cks proteins are overexpressed in many types of human cancers and this often correlates with increased tumor aggressiveness. Previously, we showed that Cks overexpression...

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Bibliografski detalji
Izdano u:Oncogene
Glavni autori: del Rincón, Sonia V., Widschwendter, Martin, Sun, Dahui, Ekholm-Reed, Susanna, Tat, John, Teixeira, Leonardo K., Ellederova, Zdenka, Grolieres, Elise, Reed, Steven I., Spruck, Charles
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4245389/
https://ncbi.nlm.nih.gov/pubmed/24858038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.137
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