Cks Overexpression Enhances Chemotherapeutic Efficacy by Overriding DNA Damage Checkpoints

Cks1 and Cks2 are adaptor-like proteins that bind many cyclin-dependent kinases (Cdks). A wealth of clinical data has shown that Cks proteins are overexpressed in many types of human cancers and this often correlates with increased tumor aggressiveness. Previously, we showed that Cks overexpression...

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Vydáno v:Oncogene
Hlavní autoři: del Rincón, Sonia V., Widschwendter, Martin, Sun, Dahui, Ekholm-Reed, Susanna, Tat, John, Teixeira, Leonardo K., Ellederova, Zdenka, Grolieres, Elise, Reed, Steven I., Spruck, Charles
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4245389/
https://ncbi.nlm.nih.gov/pubmed/24858038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.137
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