Cks Overexpression Enhances Chemotherapeutic Efficacy by Overriding DNA Damage Checkpoints

Cks1 and Cks2 are adaptor-like proteins that bind many cyclin-dependent kinases (Cdks). A wealth of clinical data has shown that Cks proteins are overexpressed in many types of human cancers and this often correlates with increased tumor aggressiveness. Previously, we showed that Cks overexpression...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Oncogene
Hauptverfasser: del Rincón, Sonia V., Widschwendter, Martin, Sun, Dahui, Ekholm-Reed, Susanna, Tat, John, Teixeira, Leonardo K., Ellederova, Zdenka, Grolieres, Elise, Reed, Steven I., Spruck, Charles
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4245389/
https://ncbi.nlm.nih.gov/pubmed/24858038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.137
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge