Cyclin-dependent kinase subunit (Cks) 1 or Cks2 overexpression overrides the DNA damage response barrier triggered by activated oncoproteins

Cyclin-dependent kinase subunit (Cks) proteins are small cyclin-dependent kinase-interacting proteins that are frequently overexpressed in breast cancer, as well as in a broad spectrum of other human malignancies. However, the mechanistic link between Cks protein overexpression and oncogenesis is st...

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Detalhes bibliográficos
Main Authors: Liberal, Vasco, Martinsson-Ahlzén, Hanna-Stina, Liberal, Jennifer, Spruck, Charles H., Widschwendter, Martin, McGowan, Clare H., Reed, Steven I.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Breast Cancer Special Feature
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286935/
https://ncbi.nlm.nih.gov/pubmed/21697511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1102434108
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