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Priming of lineage-specifying genes by Bcl11b is required for lineage choice in post-selection thymocytes
T-lineage committed precursor thymocytes are screened by a fate-determination process mediated via T cell receptor (TCR) signals for differentiation into distinct lineages. However, it remains unclear whether any antecedent event is required to couple TCR signals with the transcriptional program gov...
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| Publicado en: | Nat Commun |
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| Main Authors: | , , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5615048/ https://ncbi.nlm.nih.gov/pubmed/28951542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00768-1 |
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