Priming of lineage-specifying genes by Bcl11b is required for lineage choice in post-selection thymocytes

T-lineage committed precursor thymocytes are screened by a fate-determination process mediated via T cell receptor (TCR) signals for differentiation into distinct lineages. However, it remains unclear whether any antecedent event is required to couple TCR signals with the transcriptional program gov...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Kojo, Satoshi, Tanaka, Hirokazu, Endo, Takaho A., Muroi, Sawako, Liu, Ye, Seo, Wooseok, Tenno, Mari, Kakugawa, Kiyokazu, Naoe, Yoshinori, Nair, Krutula, Moro, Kazuyo, Katsuragi, Yoshinori, Kanai, Akinori, Inaba, Toshiya, Egawa, Takeshi, Venkatesh, Byrappa, Minoda, Aki, Kominami, Ryo, Taniuchi, Ichiro
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5615048/
https://ncbi.nlm.nih.gov/pubmed/28951542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00768-1
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