טוען...
Epigenetic Thpok silencing limits the time window to choose CD4(+) helper-lineage fate in the thymus
CD4(+) helper and CD8(+) cytotoxic T cells differentiate from common precursors in the thymus after T-cell receptor (TCR)-mediated selection. Commitment to the helper lineage depends on persistent TCR signals and expression of the ThPOK transcription factor, whereas a ThPOK cis-regulatory element, T...
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| Main Authors: | , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
European Molecular Biology Organization
2013
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3630353/ https://ncbi.nlm.nih.gov/pubmed/23481257 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.47 |
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