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Distinct requirement of Runx complexes for TCRβ enhancer activation at distinct developmental stages
A TCRβ enhancer, known as the Eβ enhancer, plays a critical role in V(D)J recombination and transcription of the Tcrb gene. However, the coordinated action of trans-acting factors in the activation of Eβ during T cell development remains uncharacterized. Here, we characterized the roles of Runx comp...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5288706/ https://ncbi.nlm.nih.gov/pubmed/28150718 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41351 |
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