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The role of the Runx transcription factors in thymocyte differentiation and in homeostasis of naive T cells

Members of the Runx family of transcriptional regulators are required for the appropriate expression of CD4 and CD8 at discrete stages of T cell development. The roles of these factors in other aspects of T cell development are unknown. We used a strategy to conditionally inactivate the genes encodi...

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Autori principali: Egawa, Takeshi, Tillman, Robert E., Naoe, Yoshinori, Taniuchi, Ichiro, Littman, Dan R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118679/
https://ncbi.nlm.nih.gov/pubmed/17646406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20070133
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