The zinc finger protein MAZR is part of the transcription factor network controlling CD4/CD8 cell fate decision of DP thymocytes

CD4/CD8 lineage specification of thymocytes is linked with coreceptor expression. Previously, the transcription factor MAZR was identified as an important regulator of Cd8 gene expression. Here we show that variegated CD8 expression by loss of Cd8 enhancers is reverted in MAZR-deficient mice, confir...

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Hlavní autoři: Sakaguchi, Shinya, Hombauer, Matthias, Bilic, Ivan, Naoe, Yoshinori, Schebesta, Alexandra, Taniuchi, Ichiro, Ellmeier, Wilfried
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365445/
https://ncbi.nlm.nih.gov/pubmed/20383150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1860
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