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The zinc finger protein MAZR is part of the transcription factor network controlling CD4/CD8 cell fate decision of DP thymocytes

CD4/CD8 lineage specification of thymocytes is linked with coreceptor expression. Previously, the transcription factor MAZR was identified as an important regulator of Cd8 gene expression. Here we show that variegated CD8 expression by loss of Cd8 enhancers is reverted in MAZR-deficient mice, confir...

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書誌詳細
主要な著者: Sakaguchi, Shinya, Hombauer, Matthias, Bilic, Ivan, Naoe, Yoshinori, Schebesta, Alexandra, Taniuchi, Ichiro, Ellmeier, Wilfried
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365445/
https://ncbi.nlm.nih.gov/pubmed/20383150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1860
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