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Determinants of the assembly and function of antibody variable domains
The antibody Fv module which binds antigen consists of the variable domains V(L) and V(H). These exhibit a conserved ß-sheet structure and comprise highly variable loops (CDRs). Little is known about the contributions of the framework residues and CDRs to their association. We exchanged conserved in...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5613017/ https://ncbi.nlm.nih.gov/pubmed/28947772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12519-9 |
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