ZNF516 suppresses EGFR by targeting the CtBP/LSD1/CoREST complex to chromatin

EGFR is required for animal development, and dysregulation of EGFR is critically implicated in malignant transformation. However, the molecular mechanism underlying the regulation of EGFR expression remains poorly explored. Here we report that the zinc-finger protein ZNF516 is a transcription repres...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Nat Commun
Hoofdauteurs: Li, Lifang, Liu, Xinhua, He, Lin, Yang, Jianguo, Pei, Fei, Li, Wanjin, Liu, Shumeng, Chen, Zhe, Xie, Guojia, Xu, Bosen, Ting, Xia, Zhang, Zihan, Jin, Tong, Liu, Xujun, Zhang, Wenting, Yuan, Shuai, Yang, Ziran, Wu, Chongyang, Zhang, Yu, Yang, Xiaohan, Yi, Xia, Liang, Jing, Shang, Yongfeng, Sun, Luyang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2017
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5612949/
https://ncbi.nlm.nih.gov/pubmed/28947780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00702-5
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items