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ICM conversion to epiblast by FGF/ERK inhibition is limited in time and requires transcription and protein degradation
Inner cell Mass (ICM) specification into epiblast (Epi) and primitive endoderm (PrE) is an asynchronous and progressive process taking place between E3.0 to E3.75 under the control of the Fibroblast Growth Factor (FGF)/Extracellular signal-Regulated Kinase (ERK) signaling pathway. Here, we have anal...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5612930/ https://ncbi.nlm.nih.gov/pubmed/28947813 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12120-0 |
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