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ICM conversion to epiblast by FGF/ERK inhibition is limited in time and requires transcription and protein degradation

Inner cell Mass (ICM) specification into epiblast (Epi) and primitive endoderm (PrE) is an asynchronous and progressive process taking place between E3.0 to E3.75 under the control of the Fibroblast Growth Factor (FGF)/Extracellular signal-Regulated Kinase (ERK) signaling pathway. Here, we have anal...

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書誌詳細
出版年:Sci Rep
主要な著者: Bessonnard, Sylvain, Coqueran, Sabrina, Vandormael-Pournin, Sandrine, Dufour, Alexandre, Artus, Jérôme, Cohen-Tannoudji, Michel
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5612930/
https://ncbi.nlm.nih.gov/pubmed/28947813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12120-0
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