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Compensation between Wnt-driven tumorigenesis and cellular responses to ribosome biogenesis inhibition in the murine intestinal epithelium

Ribosome biogenesis inhibition causes cell cycle arrest and apoptosis through the activation of tumor suppressor-dependent surveillance pathways. These responses are exacerbated in cancer cells, suggesting that targeting ribosome synthesis may be beneficial to patients. Here, we characterize the eff...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Principais autores: Raveux, Aurélien, Stedman, Aline, Coqueran, Sabrina, Vandormael-Pournin, Sandrine, Owens, Nick, Romagnolo, Béatrice, Cohen-Tannoudji, Michel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7493937/
https://ncbi.nlm.nih.gov/pubmed/32355182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-0548-6
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