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Studies of Drug Interactions with Alpha1-Acid Glycoprotein by Using On-Line Immunoextraction and High-Performance Affinity Chromatography

A method that combined on-line immunoextraction with high-performance affinity chromatography was developed to examine the binding of drugs with α(1)-acid glycoprotein (AGP). Affinity microcolumns containing immobilized polyclonal anti-AGP antibodies were developed that had a capture efficiency of u...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:J Chromatogr A
المؤلفون الرئيسيون: Bi, Cong, Matsuda, Ryan, Zhang, Chenhua, Isingizwe, Zitha, Clarke, William, Hage, David S.
التنسيق: Artigo
اللغة:Inglês
منشور في: 2017
الموضوعات:
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC5610944/
https://ncbi.nlm.nih.gov/pubmed/28886937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chroma.2017.08.073
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