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Analysis of Free Drug Fractions in Serum by Ultrafast Affinity Extraction and Two-Dimensional Affinity Chromatography using α(1)-Acid Glycoprotein Microcolumns

In the circulatory system, many drugs are reversibly bound to serum proteins such as human serum albumin (HSA) and alpha1-acid glycoprotein (AGP), resulting in both free and protein-bound fractions for these drugs. This report examined the use of microcolumns containing immobilized AGP for the measu...

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書目詳細資料
發表在:J Chromatogr A
Main Authors: Bi, Cong, Zheng, Xiwei, Hage, David S.
格式: Artigo
語言:Inglês
出版: 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4724389/
https://ncbi.nlm.nih.gov/pubmed/26797422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chroma.2015.12.084
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