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Analysis of Free Drug Fractions in Serum by Ultrafast Affinity Extraction and Two-Dimensional Affinity Chromatography using α(1)-Acid Glycoprotein Microcolumns
In the circulatory system, many drugs are reversibly bound to serum proteins such as human serum albumin (HSA) and alpha1-acid glycoprotein (AGP), resulting in both free and protein-bound fractions for these drugs. This report examined the use of microcolumns containing immobilized AGP for the measu...
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| 出版年: | J Chromatogr A |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4724389/ https://ncbi.nlm.nih.gov/pubmed/26797422 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chroma.2015.12.084 |
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