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Analysis of Free Fractions for Chiral Drugs Using Ultrafast Extraction and Multi-Dimensional High-Performance Affinity Chromatography
A multi-dimensional chromatographic approach was developed to measure the free fractions of drug enantiomers in samples that also contained a binding protein or serum. This method, which combined ultrafast affinity extraction with a chiral stationary phase, was demonstrated using the drug warfarin a...
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| Główni autorzy: | , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2013
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3812820/ https://ncbi.nlm.nih.gov/pubmed/23979112 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3an01315d |
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