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ON-COLUMN ENTRAPMENT OF ALPHA(1)-ACID GLYCOPROTEIN FOR STUDIES OF DRUG-PROTEIN BINDING BY HIGH-PERFORMANCE AFFINITY CHROMATOGRAPHY
An on-column approach for protein entrapment was developed to immobilize alpha(1)-acid glycoprotein (AGP) for drug-protein binding studies based on high-performance affinity chromatography. Soluble AGP was physically entrapped by using microcolumns that contained hydrazide-activated porous silica an...
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| Foilsithe in: | Anal Bioanal Chem |
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| Main Authors: | , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
2016
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4958572/ https://ncbi.nlm.nih.gov/pubmed/27289464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-016-9677-7 |
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