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CHARACTERIZATION OF DRUG INTERACTIONS WITH SERUM PROTEINS BY USING HIGH-PERFORMANCE AFFINITY CHROMATOGRAPHY

The binding of drugs with serum proteins can affect the activity, distribution, rate of excretion, and toxicity of pharmaceutical agents in the body. One tool that can be used to quickly analyze and characterize these interactions is high-performance affinity chromatography (HPAC). This review shows...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hage, David S., Anguizola, Jeanethe, Barnaby, Omar, Jackson, Abby, Yoo, Michelle J., Papastavros, Efthimia, Pfaunmiller, Erika, Sobansky, Matt, Tong, Zenghan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174051/
https://ncbi.nlm.nih.gov/pubmed/21395530
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