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Entrapment of Alpha(1)-Acid Glycoprotein in High-Performance Affinity Columns for Drug-Protein Binding Studies
A slurry-based method was developed for the entrapment of alpha(1)-acid glycoprotein (AGP) for use in high-performance affinity chromatography to study drug interactions with this serum protein. Entrapment was achieved based on the physical containment of AGP in hydrazide-activated porous silica sup...
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| izdano v: | J Chromatogr B Analyt Technol Biomed Life Sci |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4862888/ https://ncbi.nlm.nih.gov/pubmed/26627938 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2015.11.021 |
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