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Entrapment of Alpha(1)-Acid Glycoprotein in High-Performance Affinity Columns for Drug-Protein Binding Studies

A slurry-based method was developed for the entrapment of alpha(1)-acid glycoprotein (AGP) for use in high-performance affinity chromatography to study drug interactions with this serum protein. Entrapment was achieved based on the physical containment of AGP in hydrazide-activated porous silica sup...

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Foilsithe in:J Chromatogr B Analyt Technol Biomed Life Sci
Main Authors: Bi, Cong, Jackson, Abby, Vargas-Badilla, John, Li, Rong, Rada, Giana, Anguizola, Jeanethe, Pfaunmiller, Erika, Hage, David S.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862888/
https://ncbi.nlm.nih.gov/pubmed/26627938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2015.11.021
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