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Analysis of Drug-Protein Binding using On-Line Immunoextraction and High-Performance Affinity Microcolumns: Studies with Normal and Glycated Human Serum Albumin
A method combining on-line immunoextraction microcolumns with high-performance affinity chromatography (HPAC) was developed and tested for use in examining drug-protein interactions with normal or modified proteins. Normal human serum albumin (HSA) and glycated HSA were used as model proteins for th...
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| Publicado no: | J Chromatogr A |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4587353/ https://ncbi.nlm.nih.gov/pubmed/26381571 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chroma.2015.09.023 |
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