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CHROMATOGRAPHIC STUDIES OF CHLORPROPAMIDE INTERACTIONS WITH NORMAL AND GLYCATED HUMAN SERUM ALBUMIN BASED ON AFFINITY MICROCOLUMNS

Sulfonylurea drugs have significant binding to proteins in blood, with most of this binding believed to occur with human serum albumin (HSA). High performance affinity chromatography and affinity microcolumns containing immobilized HSA were used to investigate binding by the sulfonylurea drug chlorp...

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Pubblicato in:J Chromatogr B Analyt Technol Biomed Life Sci
Autori principali: Tao, Pingyang, Li, Zhao, Matsuda, Ryan, Hage, David S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6163082/
https://ncbi.nlm.nih.gov/pubmed/30205233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2018.09.001
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