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HIGH-PERFORMANCE AFFINITY CHROMATOGRAPHIC STUDIES OF REPAGLINIDE AND NATEGLINIDE INTERACTIONS WITH NORMAL AND GLYOXAL- OR METHYLGLYOXAL-MODIFIED HUMAN ALBUMIN SERUM

During diabetes human serum albumin (HSA), an important drug transport protein, can be modified by agents such as glyoxal (Go) and methylglyoxal (MGo) to form advanced glycation end-products. High-performance affinity microcolumns and zonal elution competition studies were used to compare interactio...

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Detalhes bibliográficos
Publicado no:J Pharm Biomed Anal
Main Authors: Ovbude, Susan T., Tao, Pingyang, Li, Zhao, Hage, David S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8169628/
https://ncbi.nlm.nih.gov/pubmed/33933705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpba.2021.114097
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