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HIGH-PERFORMANCE AFFINITY CHROMATOGRAPHIC STUDIES OF REPAGLINIDE AND NATEGLINIDE INTERACTIONS WITH NORMAL AND GLYOXAL- OR METHYLGLYOXAL-MODIFIED HUMAN ALBUMIN SERUM

During diabetes human serum albumin (HSA), an important drug transport protein, can be modified by agents such as glyoxal (Go) and methylglyoxal (MGo) to form advanced glycation end-products. High-performance affinity microcolumns and zonal elution competition studies were used to compare interactio...

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Bibliografiska uppgifter
I publikationen:J Pharm Biomed Anal
Huvudupphovsmän: Ovbude, Susan T., Tao, Pingyang, Li, Zhao, Hage, David S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2021
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8169628/
https://ncbi.nlm.nih.gov/pubmed/33933705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpba.2021.114097
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