Llwytho...
Distinct Solubility and Cytotoxicity Regimes of Paclitaxel-Loaded Cationic Liposomes at Low and High Drug Content Revealed by Kinetic Phase Behavior and Cancer Cell Viability Studies
Lipid-based particles are used worldwide in clinical trials as carriers of hydrophobic paclitaxel (PTXL) for cancer chemotherapy, albeit with little improvement over the standard-of-care. Improving efficacy requires an understanding of intramembrane interactions between PTXL and lipids to enhance PT...
Wedi'i Gadw mewn:
Cyhoeddwyd yn: | Biomaterials |
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Prif Awduron: | , , , , , |
Fformat: | Artigo |
Iaith: | Inglês |
Cyhoeddwyd: |
2017
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Pynciau: | |
Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5610109/ https://ncbi.nlm.nih.gov/pubmed/28889081 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2017.08.026 |
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