Synthesis of Linear and Cyclic Peptide-PEG-Lipids for Stabilization and Targeting of Cationic Liposome–DNA Complexes

Because nucleic acids (NAs()) have immense potential value as therapeutics, the development of safe and effective synthetic NA vectors continues to attract much attention. In vivo applications of NA vectors require stabilized, nanometer-scale particles, but the commonly used approaches of steric sta...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem Lett
Main Authors: Ewert, Kai K., Kotamraju, Venkata Ramana, Majzoub, Ramsey N., Steffes, Victoria M., Wonder, Emily A., Teesalu, Tambet, Ruoslahti, Erkki, Safinya, Cyrus R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4775344/
https://ncbi.nlm.nih.gov/pubmed/26874401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2016.01.079
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