Gene methylation biomarkers in sputum as a classifier for lung cancer risk

CT screening for lung cancer reduces mortality, but will cost Medicare ∼2 billion dollars due in part to high false positive rates. Molecular biomarkers could augment current risk stratification used to select smokers for screening. Gene methylation in sputum reflects lung field cancerization that r...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Leng, Shuguang, Wu, Guodong, Klinge, Donna M., Thomas, Cynthia L., Casas, Elia, Picchi, Maria A., Stidley, Christine A., Lee, Sandra J., Aisner, Seena, Siegfried, Jill M., Ramalingam, Suresh, Khuri, Fadlo R., Karp, Daniel D., Belinsky, Steven A.
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2017
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5609978/
https://ncbi.nlm.nih.gov/pubmed/28969046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19255
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