Gene methylation biomarkers in sputum as a classifier for lung cancer risk

CT screening for lung cancer reduces mortality, but will cost Medicare ∼2 billion dollars due in part to high false positive rates. Molecular biomarkers could augment current risk stratification used to select smokers for screening. Gene methylation in sputum reflects lung field cancerization that r...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Leng, Shuguang, Wu, Guodong, Klinge, Donna M., Thomas, Cynthia L., Casas, Elia, Picchi, Maria A., Stidley, Christine A., Lee, Sandra J., Aisner, Seena, Siegfried, Jill M., Ramalingam, Suresh, Khuri, Fadlo R., Karp, Daniel D., Belinsky, Steven A.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5609978/
https://ncbi.nlm.nih.gov/pubmed/28969046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19255
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