Metformin selectively targets redox control of complex I energy transduction

Many guanide-containing drugs are antihyperglycaemic but most exhibit toxicity, to the extent that only the biguanide metformin has enjoyed sustained clinical use. Here, we have isolated unique mitochondrial redox control properties of metformin that are likely to account for this difference. In pri...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Redox Biol
Κύριοι συγγραφείς: Cameron, Amy R., Logie, Lisa, Patel, Kashyap, Erhardt, Stefan, Bacon, Sandra, Middleton, Paul, Harthill, Jean, Forteath, Calum, Coats, Josh T., Kerr, Calum, Curry, Heather, Stewart, Derek, Sakamoto, Kei, Repiščák, Peter, Paterson, Martin J., Hassinen, Ilmo, McDougall, Gordon, Rena, Graham
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Elsevier 2017
Θέματα:
Research Paper
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5609876/
https://ncbi.nlm.nih.gov/pubmed/28942196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.08.018
Ετικέτες: Προσθήκη ετικέτας
Δεν υπάρχουν, Καταχωρήστε ετικέτα πρώτοι!

Παρόμοια τεκμήρια