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Molecular mechanism of action of metformin: old or new insights?

Metformin is the first-line drug treatment for type 2 diabetes. Globally, over 100 million patients are prescribed this drug annually. Metformin was discovered before the era of target-based drug discovery and its molecular mechanism of action remains an area of vigorous diabetes research. An improv...

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Autores principales: Rena, Graham, Pearson, Ewan R., Sakamoto, Kei
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer Berlin Heidelberg 2013
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3737434/
https://ncbi.nlm.nih.gov/pubmed/23835523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-013-2991-0
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