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Origins of the enhanced affinity of RNA-protein interactions triggered by RNA phosphorodithioate backbone modification()
The well-characterized interaction between the MS2 coat protein and its cognate RNA hairpin was used to evaluate changes in affinity as a result of phosphorodithioate (PS2) replacing phosphate by biolayer interferometry (BLI). A structure-based analysis of the data provides insights into the origins...
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| Publicado no: | Chem Commun (Camb) |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5608642/ https://ncbi.nlm.nih.gov/pubmed/28868553 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7cc05722a |
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