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Origins of the enhanced affinity of RNA-protein interactions triggered by RNA phosphorodithioate backbone modification()

The well-characterized interaction between the MS2 coat protein and its cognate RNA hairpin was used to evaluate changes in affinity as a result of phosphorodithioate (PS2) replacing phosphate by biolayer interferometry (BLI). A structure-based analysis of the data provides insights into the origins...

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書目詳細資料
發表在:Chem Commun (Camb)
Main Authors: Yang, Xianbin, Abeydeera, N. Dinuka, Liu, Feng-Wu, Egli, Martin
格式: Artigo
語言:Inglês
出版: 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5608642/
https://ncbi.nlm.nih.gov/pubmed/28868553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7cc05722a
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