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The histone variant macroH2A confers functional robustness to the intestinal stem cell compartment

A stem cell’s epigenome directs cell fate during development, homeostasis, and regeneration. Epigenetic dysregulation can lead to inappropriate cell fate decisions, aberrant cell function, and even cancer. The histone variant macroH2A has been shown to influence gene expression, guide cell fate, and...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Cedeno, Ryan James, Nakauka-Ddamba, Angela, Yousefi, Maryam, Sterling, Stephanie, Leu, Nicolae Adrian, Li, Ning, Pehrson, John R., Lengner, Christopher Joachim
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5608326/
https://ncbi.nlm.nih.gov/pubmed/28934364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0185196
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