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The histone variant macroH2A confers functional robustness to the intestinal stem cell compartment

A stem cell’s epigenome directs cell fate during development, homeostasis, and regeneration. Epigenetic dysregulation can lead to inappropriate cell fate decisions, aberrant cell function, and even cancer. The histone variant macroH2A has been shown to influence gene expression, guide cell fate, and...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Cedeno, Ryan James, Nakauka-Ddamba, Angela, Yousefi, Maryam, Sterling, Stephanie, Leu, Nicolae Adrian, Li, Ning, Pehrson, John R., Lengner, Christopher Joachim
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5608326/
https://ncbi.nlm.nih.gov/pubmed/28934364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0185196
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