The histone variant macroH2A confers functional robustness to the intestinal stem cell compartment

A stem cell’s epigenome directs cell fate during development, homeostasis, and regeneration. Epigenetic dysregulation can lead to inappropriate cell fate decisions, aberrant cell function, and even cancer. The histone variant macroH2A has been shown to influence gene expression, guide cell fate, and...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Cedeno, Ryan James, Nakauka-Ddamba, Angela, Yousefi, Maryam, Sterling, Stephanie, Leu, Nicolae Adrian, Li, Ning, Pehrson, John R., Lengner, Christopher Joachim
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5608326/
https://ncbi.nlm.nih.gov/pubmed/28934364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0185196
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