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Guanylate Binding Proteins Regulate Inflammasome Activation in Response to Hyperinjected Yersinia Translocon Components

Gram-negative bacterial pathogens utilize virulence-associated secretion systems to inject, or translocate, effector proteins into host cells to manipulate cellular processes and promote bacterial replication. However, translocated bacterial products are sensed by nucleotide binding domain and leuci...

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Библиографические подробности
Опубликовано в: :Infect Immun
Главные авторы: Zwack, Erin E., Feeley, Eric M., Burton, Amanda R., Hu, Baofeng, Yamamoto, Masahiro, Kanneganti, Thirumala-Devi, Bliska, James B., Coers, Jörn, Brodsky, Igor E.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5607426/
https://ncbi.nlm.nih.gov/pubmed/28784930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00778-16
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