Guanylate Binding Proteins Regulate Inflammasome Activation in Response to Hyperinjected Yersinia Translocon Components

Gram-negative bacterial pathogens utilize virulence-associated secretion systems to inject, or translocate, effector proteins into host cells to manipulate cellular processes and promote bacterial replication. However, translocated bacterial products are sensed by nucleotide binding domain and leuci...

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Vydáno v:Infect Immun
Hlavní autoři: Zwack, Erin E., Feeley, Eric M., Burton, Amanda R., Hu, Baofeng, Yamamoto, Masahiro, Kanneganti, Thirumala-Devi, Bliska, James B., Coers, Jörn, Brodsky, Igor E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2017
Témata:
Host Response and Inflammation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5607426/
https://ncbi.nlm.nih.gov/pubmed/28784930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00778-16
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